Switzerland - Japan Workshop

New Directions in Cellular and Tissue Biomechanics

 

Les Diablerets, Switzerland

September 24-28, 2001

 

Sponsored byF

@Swiss National Science Foundation

@Japan Society for the Promotion of Science

Organized byF

@Swiss Federal Institute of Technology - Lausanne

@Japan Society of Mechanical Engineers, Division of Bioengineering

 

 

 

Scientific Committee

 

Switzerland:

Andreas Engel

Biozentrum, University of Basel

Ernst Hunziker

M.E. Muller Institute for Biomechanics, University of Bern

Peter Niederer

Institute of Biomedical Engineering - Swiss Federal Institute of Technology, Zurich

Jean-Jacques Meister (co-chair)

Biomedical Engineering Laboratory - Swiss Federal Institute of Technology, Lausanne

 

Japan:

Toshiaki Hara

Faculty of Engineering, Niigata University

Kozaburo Hayashi (co-chair)

Graduate School of Engineering Science, Osaka University

Masaaki Sato

Graduate School of Engineering, Tohoku University

Kazuo Tanishita

Faculty of Science and Technology, Keio University

 

Secretariat

For any information, please contact:

Biomedical Engineering Laboratory

Swiss Federal Institute of Technology

Attn to Yvette Ga11ay

PSE - Ecublens

1015 Lausanne

Tel: +41 21 693 83 45

Fax: +41 21 693 83 05

E-mail: yvette.gallay@epfl.ch

 

 

 

Scientific Program

 

Vascular Biomechanics: September 25, 8:30 - 12:30

Chair: M. Sato and P. Niederer

 

8:30

Karino T. (Hokkaido University), Wada S., Naiki T.

"Flow-dependent concentration polarization of lipoproteins" as a localizing mechanism of vascular diseases

 

9:10

Stergiopulos N. (Swiss Federal Institute of Technology, Lausanne)

Biomechanics of arterial remodeling: from basic science to applied vascular technologies

 

9:50 - 10:10

Coffee break

 

10:10

Hayashi K. (Osaka University), Makino A., Kakoi D., Miyazaki H.

Arterial wall remodeling developed by blood flow and blood flow changes

 

10:30

Matsumoto T. (Tohoku University), Sato M.

Theoretical and experimental analysis of stress and strain distribution in the artery wall having material inhomogeneity

 

10:50

Beny J.-L. (Geneva University)

Information networks in the arterial wall

 

11:10

Ogasawara Y. (Kawasaki Medical School), Kajita T., Matsumoto T., Kajiya F.

Spatial correlation of mitochondrial redox state and microcirculatory flow distribution in beating rat heart

 

11:30

Tsujioka K. (Kawasaki Medical School), Asahara H.

Effect of local blood flow condition on production of nitric oxide by vascular endothelial cell and expression of eNOS

 

11:50

Quarteroni A. (Swiss Federal Institute of Technology, Lausanne)

Multiscale models for the simulation of vascular flow

 

12:10

Yamaguchi T. (Nagoya Institute of Technology), Mori D., Hayasaka T.

Development of a patient specific modeling system for clinical cardiovascular flow-wall interaction studies

 

12:30-14:00

Lunch

 

 

New Areas in Biomechanics I: September 25, 14:00 - 18:20

Chair: M. Sokabe and E. Hunziker

 

14:00

Yanagida T. (Osaka University)

Single molecule dynamics and mechanics

 

14:40

Engel A. (Basel University)

Imaging and manipulating membrane proteins using the atomic force microscope

 

15:20

Wada H. (Tohoku University)

Psychological characteristics of our hearing are mainly determined by the motility of sensory cells

 

16:00- 16:20

Coffee break

 

16:20

Verkhovsky A. (Swiss Federal Institute of Technology, Lausanne)

Moving cells: what moves, when and where

 

17:00

Danuser G. (Swiss Federal Institute of Technology, Zurich)

Cell shape and motility is controlled by actin flow dynamics

 

17:40

Keller H. (Bern University)

Mechanisms of protrusion and locomotion

 

 

Cellular Biomechanics: September 26, 8:30 - 12:30

Chair: K. Tsujioka and A. Engel

 

8:30

Kamiya A. (Nihon University)

System physiology of oxygen transport and related cellular biomechanics

 

9:10

Sokabe M. (Nagoya University)

Mechanotransduction in endothelial cells: SA channel, integrin and cytoskeleton

 

9:50 - 10:10

Coffee break

 

10:10

Meister J.-J. (Swiss Federal Institute of Technology, Lausanne)

Mechanical properties of endothelial cell cytoplasm and nucleus

 

10:30

Ando J. (University of Tokyo)

Calcium signaling of fluid shear stress in vascular endothelial cells

 

10:50

Sato M. (Tohoku University), Sakamoto N., Ohashi T., Iwano A.

Effect of O2/CO2 gas condition on calcium and morphological responses of cultured endothelial cells to shear stress

 

11:10

Tanishita K. (Keio University)

Enhance macro-molecule transport due to the shear stress stimulus

 

11:30

Bochaton-Piallat M.-L. (Geneva University)

Role of smooth muscle cell in atheromatosis and restenosis

 

11:50

Quinn T. (Orthopedic Hospital and Swiss Federal Institute of Technology, Lausanne)

Relationship between mechanical compression, solute transport, and cell metabolism in cartilage:@potential applications to tissue engineering

 

12:10

Adachi T. (Kobe University), Sato K., Tomita Y.

Calcium signaling response in osteoblastic cells to mechanical stimulus by micropipette

 

12:30-14:00

Lunch

 

 

New Areas in Biomechanics II: September 27, 8:30 - 12:10

Chair: K. Tanishita and G. Danuser

 

8F30

Kajiya F. (Okayama Universityj

Application of synchrotron radiationiSpring-8jto cardiovascular biomechanics

 

9F10

Margaritondo G. (Swiss Federal Institute of Technology, Lausanne)

Synchrotron light in molecular biology; from characterization to nanofabrication

 

9F50-10:10

Coffee break

 

10F10

Martin I. (Basel University)

Mechanobiology and biomechanics of tissue engineered cartilage

 

10F50

Ushida T. (University of Tokyo), Tateishi TD

Physical stimulation to chondrocytes for tissue-engineered cartilage regeneration

 

11F30

Kucera P. (Lausanne University)

Spatial and temporal organization of enteric pacemakers

 

12:30-14:00

Lunch

 

 

Orthopedic Biomechanics, September 27, 14F00-18F00

Chair: T. Hara and T. Quinn

 

14F00

Hunziker E. (Bern Universityj

The potential of the synovium for cartilage repair

 

14F40

Tanaka E. (Nagoya University), Yamamoto S.

A mathematical model of bone remodeling process

 

15F20

Niederer P. (Swiss Federal Institute of TechnologyCZurich)

Micromechanics of minor cervical spine injuries

 

16:00 - 16:20

Coffee break

 

16F20

Zysset P. (Swiss Federal Institute of Technology, Lausanne)

Morphological and mechanical properties of bone structural units

 

16F40

Takakuda K. (Tokyo Medical and Dental University), Matsumoto H.CKanaya T., Koyama T., Miyairi H.

Adaptive remodeling of bone under mechanical stimuli

 

17F00

Tanaka M. (Osaka University), Todoh M., Ebara S.

Computation analysis of idiopathic scoliosisF A viewpoint of inconsistent growth between hard and soft tissue components

 

17F20

Murakami T. (Kyushu University), Sawae Y., Ihara M.

The protective mechanism of articular cartilage to severe loadingFRoles of lubricants, Cartilage surface layer, extracellular matrix and chondrocyte

 

17F40

Yasui T. (Osaka University), Nakamoto K., Tohno Y., Araki T.

Laser induced dynamic emission sensitive to the conformation of tissue collagen

 

 

Commented poster session, September 28, 8:30 - 10:10

Chair: T. Murakami and N. Stergiopulos

 

Cellular Biomechanics

 

8F30

Sugawara M. (Tohoku University), Wada H.

Elastic properties of lateral wall and force production of the outer hair cell: Theoretical consideration

 

8F34

Kataoka N. (Kawasaki Medical School), Ogasawara Y., Tsujioka K., Kajiya F.

Monocyte adhesion induces the change of the mechanical properties of endothelial cells measured with an atomic force microscope

 

8F38

Kurata K. (Kyushu University and University of Turku), Uemura T., Nemoto A., Tateishi T., Murakami T., Higaki H., Miura H., Iwamoto Y.

Mechanical strain enhances bone-resorbing activity and mRNA expressions of marker enzymes in highly enriched osteoclast culture

 

8F42

Miyazaki H. (Osaka University), Hasegawa Y., Hayashi K.

Tensile properties of synthetic and contractile phenotypes of vascular smooth muscle cells

 

8F46

Dehghani Zadeth A. (Bern University)

The role of surface glycoproteins (CD43, CD45) and cytoskeletal components in the development of PMN polarity

 

8F50

Laurent V. (Swiss Federal Institute of Technology. Lausanne)

Partitioning the cytoskeleton mechanical response into cytosolic and cortical compartments: concept, experimental validation and preliminary applications

 

8F54

Ponti A. (Swiss Federal Institute of Technology, Zurich), Danuser G.

Actin flow dynamics measured by fluorescence speckle microscopy

 

8F58

Hao H. (University of Geneva)

Phenotypic heterogeneity of arterial smooth muscle cells

 

9F02

Yamada H. (Kyushu Institute of Technology), Takemasa T., Yamaguchi T.

Numerical simulation of the orientation of cultured cells and intracellular stress fibers under cyclic stretch: Prediction of substrate deformation from orientation data

 

Vascular biomechanics

 

9F06

Kato Y. (Tohoku University & Riken), Mastumoto T., Kumagai K., Akimoto H., Tabayashi K., Sato M.

Construction of three-dimensional finite element models of thoracic aortic aneurysms and stress analysis in the aortic walls

 

9:10

Formaggia L. (Swiss Federal Institute of Technology, Lausanne)

Wave propagation in arteries with the presence of prosthesis

 

9F14

Zulliger M. (Swiss Federal Institute of Technology, Laussanneej

Short-term in vitro adaptation of porcine carotid artery elastic module to high and low transmural pressures

 

9F18

Zunino P. (Swiss Federal Institute of TechnologyCLausanne)

Computational modeling of mass transport in the arterial wall

 

9F22

Kobayashi S. (Shinshu University), Horie T., Morikawa H., Tang D., Ku D. N.

Hemodynamics and wall compression in high grade asymmetric arterial stenoses

 

Orthopedic Biomechanics

 

9:26

Tsubota K. (Kobe University and Riken), Adachi T., Tomita Y.

Simulation study on trabecular surface remodeling using digital image-based model

 

9:30

Yamamoto S. (Nagoya University), Tanaka E., Harada A., Mizuno M.

Evaluation of mechanical and morphological factors of hip fracture

 

9:34

Park Y. D. (Bern University)

Preparation and characterization of bioactive hyaluronic acid based hydrogel

 

9:38

Sugimoto M. (Bern University)

Gene expression of synoviocytes in 3D culture

 

9:42

Buechler P. (Orthopedic Hospital and Swiss Federal Institute of Technology, Lausanne)

Humeral head design: Biomechanical comparison of two prostheses

 

9:46

Koseki M. (Tokyo Institute of Technology), Inou N., Maki K.

Individual stress analysis of the human mandible under a biting condition

 

9:50

Morita Y. (Kyoto University), Tomita N., Aoki H., Wakitani S., Tamada Y., Harada Y., Suguro T., Ikeuchi K.

Visco-elastic properties of regenerated cartilage tissue using fibroin sponge

 

9:54

Pioletti D. (Orthopedic Hospital and Swiss Federal Institute of Technology, Lausanne)

Orthopaedic implant as drug delivery system

 

Others

 

9:58

Koike T. (Tohoku University), Wada H., Kobayashi T.

Sound transmission characteristics of human and guinea pig middle ears: A finite-element method analysis

 

10:02

Dorri F. (Swiss Federal Institute of Technology, Zurich)

Fiber Orientation and fiber forces in the human myocardium

 

10:04

Bertrand D. (University of Geneva), Renaud P.

Strain gauges for ocular pressure monitoring

 

 


All Rights Reserved, Copyright (C) 2001, The Japan Society of Mechanical Engineers. Bioengineering Division