Switzerland - Japan Workshop
New Directions in Cellular and Tissue Biomechanics
Les Diablerets, Switzerland
September 24-28, 2001
Swiss National Science Foundation
Japan Society for the Promotion of Science
Swiss Federal Institute of Technology - Lausanne
Japan Society of Mechanical Engineers, Division of Bioengineering
Biozentrum, University of Basel
M.E. Muller Institute for Biomechanics, University of Bern
Institute of Biomedical Engineering - Swiss Federal Institute of Technology, Zurich
Jean-Jacques Meister (co-chair)
Biomedical Engineering Laboratory - Swiss Federal Institute of Technology, Lausanne
Faculty of Engineering, Niigata University
Kozaburo Hayashi (co-chair)
Graduate School of Engineering Science, Osaka University
Graduate School of Engineering, Tohoku University
Faculty of Science and Technology, Keio University
For any information, please contact:
Biomedical Engineering Laboratory
Swiss Federal Institute of Technology
Attn to Yvette Ga11ay
PSE - Ecublens
Tel: +41 21 693 83 45
Fax: +41 21 693 83 05
Vascular Biomechanics: September 25, 8:30 - 12:30
Chair: M. Sato and P. Niederer
Karino T. (Hokkaido University), Wada S., Naiki T.
"Flow-dependent concentration polarization of lipoproteins" as a localizing mechanism of vascular diseases
Stergiopulos N. (Swiss Federal Institute of Technology, Lausanne)
Biomechanics of arterial remodeling: from basic science to applied vascular technologies
9:50 - 10:10
Hayashi K. (Osaka University), Makino A., Kakoi D., Miyazaki H.
Arterial wall remodeling developed by blood flow and blood flow changes
Matsumoto T. (Tohoku University), Sato M.
Theoretical and experimental analysis of stress and strain distribution in the artery wall having material inhomogeneity
Beny J.-L. (Geneva University)
Information networks in the arterial wall
Ogasawara Y. (Kawasaki Medical School), Kajita T., Matsumoto T., Kajiya F.
Spatial correlation of mitochondrial redox state and microcirculatory flow distribution in beating rat heart
Tsujioka K. (Kawasaki Medical School), Asahara H.
Effect of local blood flow condition on production of nitric oxide by vascular endothelial cell and expression of eNOS
Quarteroni A. (Swiss Federal Institute of Technology, Lausanne)
Multiscale models for the simulation of vascular flow
Yamaguchi T. (Nagoya Institute of Technology), Mori D., Hayasaka T.
Development of a patient specific modeling system for clinical cardiovascular flow-wall interaction studies
New Areas in Biomechanics I: September 25, 14:00 - 18:20
Chair: M. Sokabe and E. Hunziker
Yanagida T. (Osaka University)
Single molecule dynamics and mechanics
Engel A. (Basel University)
Imaging and manipulating membrane proteins using the atomic force microscope
Wada H. (Tohoku University)
Psychological characteristics of our hearing are mainly determined by the motility of sensory cells
Verkhovsky A. (Swiss Federal Institute of Technology, Lausanne)
Moving cells: what moves, when and where
Danuser G. (Swiss Federal Institute of Technology, Zurich)
Cell shape and motility is controlled by actin flow dynamics
Keller H. (Bern University)
Mechanisms of protrusion and locomotion
Cellular Biomechanics: September 26, 8:30 - 12:30
Chair: K. Tsujioka and A. Engel
Kamiya A. (Nihon University)
System physiology of oxygen transport and related cellular biomechanics
Sokabe M. (Nagoya University)
Mechanotransduction in endothelial cells: SA channel, integrin and cytoskeleton
9:50 - 10:10
Meister J.-J. (Swiss Federal Institute of Technology, Lausanne)
Mechanical properties of endothelial cell cytoplasm and nucleus
Ando J. (University of Tokyo)
Calcium signaling of fluid shear stress in vascular endothelial cells
Sato M. (Tohoku University), Sakamoto N., Ohashi T., Iwano A.
Effect of O2/CO2 gas condition on calcium and morphological responses of cultured endothelial cells to shear stress
Tanishita K. (Keio University)
Enhance macro-molecule transport due to the shear stress stimulus
Bochaton-Piallat M.-L. (Geneva University)
Role of smooth muscle cell in atheromatosis and restenosis
Quinn T. (Orthopedic Hospital and Swiss Federal Institute of Technology, Lausanne)
Relationship between mechanical compression, solute transport, and cell metabolism in cartilage: potential applications to tissue engineering
Adachi T. (Kobe University), Sato K., Tomita Y.
Calcium signaling response in osteoblastic cells to mechanical stimulus by micropipette
New Areas in Biomechanics II: September 27, 8:30 - 12:10
Chair: K. Tanishita and G. Danuser
Kajiya F. (Okayama University）
Application of synchrotron radiation（Spring-8）to cardiovascular biomechanics
Margaritondo G. (Swiss Federal Institute of Technology, Lausanne)
Synchrotron light in molecular biology; from characterization to nanofabrication
Martin I. (Basel University)
Mechanobiology and biomechanics of tissue engineered cartilage
Ushida T. (University of Tokyo), Tateishi T．
Physical stimulation to chondrocytes for tissue-engineered cartilage regeneration
Kucera P. (Lausanne University)
Spatial and temporal organization of enteric pacemakers
Orthopedic Biomechanics, September 27, 14：00-18：00
Chair: T. Hara and T. Quinn
Hunziker E. (Bern University）
The potential of the synovium for cartilage repair
Tanaka E. (Nagoya University), Yamamoto S.
A mathematical model of bone remodeling process
Niederer P. (Swiss Federal Institute of Technology，Zurich)
Micromechanics of minor cervical spine injuries
16:00 - 16:20
Zysset P. (Swiss Federal Institute of Technology, Lausanne)
Morphological and mechanical properties of bone structural units
Takakuda K. (Tokyo Medical and Dental University), Matsumoto H.，Kanaya T., Koyama T., Miyairi H.
Adaptive remodeling of bone under mechanical stimuli
Tanaka M. (Osaka University), Todoh M., Ebara S.
Computation analysis of idiopathic scoliosis： A viewpoint of inconsistent growth between hard and soft tissue components
Murakami T. (Kyushu University), Sawae Y., Ihara M.
The protective mechanism of articular cartilage to severe loading：Roles of lubricants, Cartilage surface layer, extracellular matrix and chondrocyte
Yasui T. (Osaka University), Nakamoto K., Tohno Y., Araki T.
Laser induced dynamic emission sensitive to the conformation of tissue collagen
Commented poster session, September 28, 8:30 - 10:10
Chair: T. Murakami and N. Stergiopulos
Sugawara M. (Tohoku University), Wada H.
Elastic properties of lateral wall and force production of the outer hair cell: Theoretical consideration
Kataoka N. (Kawasaki Medical School), Ogasawara Y., Tsujioka K., Kajiya F.
Monocyte adhesion induces the change of the mechanical properties of endothelial cells measured with an atomic force microscope
Kurata K. (Kyushu University and University of Turku), Uemura T., Nemoto A., Tateishi T., Murakami T., Higaki H., Miura H., Iwamoto Y.
Mechanical strain enhances bone-resorbing activity and mRNA expressions of marker enzymes in highly enriched osteoclast culture
Miyazaki H. (Osaka University), Hasegawa Y., Hayashi K.
Tensile properties of synthetic and contractile phenotypes of vascular smooth muscle cells
Dehghani Zadeth A. (Bern University)
The role of surface glycoproteins (CD43, CD45) and cytoskeletal components in the development of PMN polarity
Laurent V. (Swiss Federal Institute of Technology. Lausanne)
Partitioning the cytoskeleton mechanical response into cytosolic and cortical compartments: concept, experimental validation and preliminary applications
Ponti A. (Swiss Federal Institute of Technology, Zurich), Danuser G.
Actin flow dynamics measured by fluorescence speckle microscopy
Hao H. (University of Geneva)
Phenotypic heterogeneity of arterial smooth muscle cells
Yamada H. (Kyushu Institute of Technology), Takemasa T., Yamaguchi T.
Numerical simulation of the orientation of cultured cells and intracellular stress fibers under cyclic stretch: Prediction of substrate deformation from orientation data
Kato Y. (Tohoku University & Riken), Mastumoto T., Kumagai K., Akimoto H., Tabayashi K., Sato M.
Construction of three-dimensional finite element models of thoracic aortic aneurysms and stress analysis in the aortic walls
Formaggia L. (Swiss Federal Institute of Technology, Lausanne)
Wave propagation in arteries with the presence of prosthesis
Zulliger M. (Swiss Federal Institute of Technology, Laussannee）
Short-term in vitro adaptation of porcine carotid artery elastic module to high and low transmural pressures
Zunino P. (Swiss Federal Institute of Technology，Lausanne)
Computational modeling of mass transport in the arterial wall
Kobayashi S. (Shinshu University), Horie T., Morikawa H., Tang D., Ku D. N.
Hemodynamics and wall compression in high grade asymmetric arterial stenoses
Tsubota K. (Kobe University and Riken), Adachi T., Tomita Y.
Simulation study on trabecular surface remodeling using digital image-based model
Yamamoto S. (Nagoya University), Tanaka E., Harada A., Mizuno M.
Evaluation of mechanical and morphological factors of hip fracture
Park Y. D. (Bern University)
Preparation and characterization of bioactive hyaluronic acid based hydrogel
Sugimoto M. (Bern University)
Gene expression of synoviocytes in 3D culture
Buechler P. (Orthopedic Hospital and Swiss Federal Institute of Technology, Lausanne)
Humeral head design: Biomechanical comparison of two prostheses
Koseki M. (Tokyo Institute of Technology), Inou N., Maki K.
Individual stress analysis of the human mandible under a biting condition
Morita Y. (Kyoto University), Tomita N., Aoki H., Wakitani S., Tamada Y., Harada Y., Suguro T., Ikeuchi K.
Visco-elastic properties of regenerated cartilage tissue using fibroin sponge
Pioletti D. (Orthopedic Hospital and Swiss Federal Institute of Technology, Lausanne)
Orthopaedic implant as drug delivery system
Koike T. (Tohoku University), Wada H., Kobayashi T.
Sound transmission characteristics of human and guinea pig middle ears: A finite-element method analysis
Dorri F. (Swiss Federal Institute of Technology, Zurich)
Fiber Orientation and fiber forces in the human myocardium
Bertrand D. (University of Geneva), Renaud P.
Strain gauges for ocular pressure monitoring